The Belfer Center's Drug Discovery platform focuses on the steps leading up to first-in-human trials, from target discovery to IND submission.
Belfer investigators complement our industry partners' clinical development expertise by bringing to the table leading-edge basic discoveries, clinical expertise and knowledge, and advanced biological models—including clinical samples and unique disease models—geared toward basic and preclinical drug development. As a result, we address a variety of critical drug-discovery needs:
- Generation and validation of hypotheses regarding responder populations
- Identification and validation of predictive, response, and pharmacodynamic biomarkers
- Identification of novel targets by leading-edge approaches
- Target validation using unique models and technology