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Drug discovery

Drug discovery

The Belfer Center's Drug Discovery platform focuses on the steps leading up to first-in-human trials, from target discovery to IND submission.

Belfer investigators complement our industry partners' clinical development expertise by bringing to the table leading-edge basic discoveries, clinical expertise and knowledge, and advanced biological models—including clinical samples and unique disease models—geared toward basic and preclinical drug development. As a result, we address a variety of critical drug-discovery needs:

  • Generation and validation of hypotheses regarding responder populations
  • Identification and validation of predictive, response, and pharmacodynamic biomarkers
  • Identification of novel targets by leading-edge approaches
  • Target validation using unique models and technology